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Research Technician

Requisition ID:  11602

Newcastle, GB

Contract Type:  Fixed Term
Working Pattern:  Full Time
Posted Date:  13-Sep-2021


We are a world class research-intensive university. We deliver teaching and learning of the highest quality. We play a leading role in economic, social and cultural development of the North East of England. Attracting and retaining high-calibre people is fundamental to our continued success.


Salary: £22,254 - £23,487 per annum

Closing Date: 11 October 2021


The Role


The experienced and motivated research technician will join the Newcastle Fibrosis Research group under the direct supervision of Dr Jack Leslie with significant guidance and support from Prof Fiona Oakley. The laboratory is a multidisciplinary research group investigating the molecular and pathological mechanisms underlying the development of organ inflammation, fibrosis and cancer. This research project will also be undertaken in collaboration with FibroFind Ltd. The research program will utilise murine and human tissue combined with histological and biochemical approaches to develop novel ex vivo models of chronic disease which will aid the discovery of novel targets and test therapeutic interventions.


This is a full time, fixed term role available for 1 year.


For any informal enquires please contact Jack Leslie, jack.leslie@newcastle.ac.uk 

Key Accountabilities

•    To deliver high impact research on the molecular biology of lung fibrosis
•    To be responsible for day-to-day management of experimental work involving in vitro, histological, biochemical and molecular approaches
•    To be responsible for collection, processing, analysis, presentation (writing, graph production, image production and oral presentations at national/international conferences) and storage of experimental data in accurate, secure, detailed and up-to-date records of all work carried out to GLP standard
•    To facilitate general management and running of the laboratory including routine laboratory cleaning, maintenance, equipment upkeep and ordering of laboratory materials
•    To facilitate the fibrosis group in other aspects of its operation including contribution to laboratory meetings, contribution to web-based activities and contribution to its public engagement activities
•    Carry out pre-clinical pathway/ target validation work, using an in vivo experimental approaches and a wide range of molecular and cell biology techniques, including: immunohistochemistry, immunocytofluorescence, FACS, ELISA, RNA extraction, RT-PCR etc, as required
•    Analyse data statistically and have a major input into both the experimental design and methodology
•    Manage his/her time effectively and work independently on a day-to-day basis, but also work closely with Project supervisors and other members of the research team
•    Attend research seminars and other departmental meetings as required. Contribute to the presentation of results to the group and to the research community in general
•    Ensure that all work done in the laboratory complies with the applicable regulations concerning biohazards and radiation
•    Arrange equipment maintenance and repair, as necessary
•    Contribute to the preparation reports and scientific publications, as requested by project co-ordinators
•    Comply with University policies, including financial regulations, equal opportunities policy, health and safety policy, promoting race equality policy, information systems security policy, data security and intellectual property rights
•    Carry out any other duties, which may arise commensurate with the grade of the post, as requested by the project co-ordinators


The Person (Essential)


Knowledge, Skills and Experience


•    Experience/Awareness of laboratory Health and Safety issues
•    An in depth understanding of cell and molecular biology with a particular focus on lung fibrosis
•    Good teamwork, excellent interpersonal, oral and written communication skills
•    Good computer skills, with the ability to graph and statistically analyse data
•    Excellent record-keeping, time management and organisational skills
•    Ability to modify and apply new methods to advance the project
•    Culture of cell lines, primary cells including tissue explants
•    RNA extraction from cells and tissue, PCR, real-time PCR (Sybr Green and molecular probe based)
•    ELISA 
•    Immunohistochemistry
•    Protein isolation
•    Demonstrable lab experience in a similar environment
•    Willingness to work outside normal hours when necessary


Attributes and Behaviour


•    Works collaboratively with others, plays a positive role in teams and establishes and grows relationships across the organisation where different skills, expertise and opinions are valued
•    Respects the expertise and contribution of others even if own opinion is different
•    Shares relevant and useful information with others
•    Keeps other team members up to date with progress
•    Willing to help others and share workloads
•    Asks others’ opinion
•    Encourages others to get involved
•    Talks about other team members in a positive way
•    Respects the value that different views bring to the team



•    A-level/HNC standard of education or equivalent in a related subject
•    BSc degree in related area (desirable)
•    MSc in relevant field (desirable)


Newcastle University is committed to being a fully inclusive Global University which actively recruits, supports and retains colleagues from all sectors of society.  We value diversity as well as celebrate, support and thrive on the contributions of all our employees and the communities they represent.  We are proud to be an equal opportunities employer and encourage applications from everybody, regardless of race, sex, ethnicity, religion, nationality, sexual orientation, age, disability, gender identity, marital status/civil partnership, pregnancy and maternity, as well as being open to flexible working practices.


The University holds a silver Athena SWAN award in recognition of our good employment practices for the advancement of gender equality. The University also holds the HR Excellence in Research award for our work to support the career development of our researchers, and is a member of the Euraxess initiative supporting researchers in Europe.


We understand how important the full employment package is to our colleagues at Newcastle University and we are committed to providing a great range of benefits and discounts for all.  You can learn more about what is available here on our Benefits Website page.

Requisition ID: 11602