Share this Job

Research Associate/Assistant

Requisition ID:  8881

Newcastle, GB

Contract Type:  Fixed Term
Working Pattern:  Full Time
Posted Date:  11-Jun-2021


We are a world class research-intensive university. We deliver teaching and learning of the highest quality. We play a leading role in economic, social and cultural development of the North East of England. Attracting and retaining high-calibre people is fundamental to our continued success.


Salary: £28,331.00 - £30,942.00 

Closing Date: 18 June 2021


The Role 


The successful applicant will join the research division of the National Renal Complement Therapeutics Centre (http://www.atypicalhus.co.uk/) and will be a key to overseeing testing of complement therapeutics in multiple models – in vitro and in vivo. The project forms part of ongoing research into developing drugs to treat complement-mediated diseases and is undertaken in collaboration with Catalyst Biosciences LTD. You will carry out production of recombinant proteins and undertake functional analysis using an array of bespoke complement assays. As part of our commitment to career development for research colleagues, the University has developed 3 levels of research role profiles.  These profiles set out firstly the generic competences and responsibilities expected of role holders at each level and secondly the general qualifications and experiences needed for entry at a particular level.

You should have significant experience in complement biology, immunology and complement haemolytic assays will be essential. Experience with SPR, protein purification and production will be essential. Experience with in vivo models would be highly desirable. 


This post is fixed term for a period of 12 Months. 


For informal enquiries contact: Kevin.Marchbank@ncl.ac.uk


Please see the web links for further details on the NRCTC and the Immunity & Inflammation theme (https://www.ncl.ac.uk/medical-sciences/research/research-themes/immunology/)
Find out more about the Faculty of Medical Sciences here: https://www.ncl.ac.uk/medical-sciences/ 


Key Accountabilities

•    Although working under the general guidance of an academic or Principal Investigator, the postholder will contribute ideas, including enhancements to the technical or methodological aspects of their studies, thus providing substantial 'added value' 
•    Develop and carry out the specified project using appropriate techniques and equipment as outlined in the personal requirements 
•    Determine appropriate methodologies for research, with advice and support where required
•    Contribute to grant applications submitted by others and in time develop own research objectives and proposals for funding 
•    Begin to write, with appropriate support, proposals for individual research funding or, where funders do not permit this, contribute to the writing of collective bids
•    Assess research findings for the need/scope for further investigations
•    Contribute to the writing up of their research for publication and dissemination, either through seminar and conference presentations or through publications
•    Present research findings, either at conferences or through publications in reputable outlets appropriate to the discipline
•    May be involved in the supervision, with guidance, of final year undergraduate research projects and in providing support to postgraduate research students or Research Assistants 
•    Will need to work with the support staff and, on occasions, with undergraduate and postgraduate students, and interact intellectually with other academic members of the Institute.
•    May contribute to events celebrating the public engagement of science/social sciences/humanities
•    Develop an awareness of University structures, policies and procedures and relevant issues in the higher education, research, social and political environment
•    Work in close collaboration with Catalyst Bioscience to develop new opportunities to expand the research.

The Person (Essential)


Knowledge, Skills and Experience 

•    Ability to work well as part of a team and rapidly acquire new skills
•    Detailed subject knowledge (PI to describe subject knowledge required) in the area of research 
•    Likelihood of advanced skills directly related to the research projects 
•    High level of analytical and problem-solving capability 
•    Ability to communicate complex information with clarity and to encourage the commitment of others 
•    Experience of research with clear transferable skills and some experience or awareness of the research environment 
•    Presentations at conferences and/or high-quality publications 
•    Significant experience in complement biology and immunology.
•    Knowledge and experience with complement haemolytic assays 
•    Knowledge and experience with SPR. 
•    Knowledge and experience in protein production and testing. 
•    Knowledge and experience in handling human blood (products)
•    Knowledge and experience in immunological assays (ELISA, Western and/or IF)


•    Experience with in vivo models would be highly desirable
•    Experience with Graphpad Prism software
•    Experience with Pymol


Attributes and Behaviour

•    Hard working
•    Good time management


•    Expert at multitasking
•    Good at team working and confident in individual working



•    A PhD in Immunology/Complement Biology For Research Associate 

•    Honors degree in Immunobiology or allied field or close to submission of PhD for Research Assistant Level.  


Newcastle University is committed to being a fully inclusive Global University which actively recruits, supports and retains staff from all sectors of society.  We value diversity as well as celebrate, support and thrive on the contributions of all our employees and the communities they represent.  We are proud to be an equal opportunities employer and encourage applications from everybody, regardless of race, sex, ethnicity, religion, nationality, sexual orientation, age, disability, gender identity, marital status/civil partnership, pregnancy and maternity, as well as being open to flexible working practices.


The University holds a silver Athena SWAN award in recognition of our good employment practices for the advancement of gender equality. The University also holds the HR Excellence in Research award for our work to support the career development of our researchers, and is a member of the Euraxess initiative supporting researchers in Europe.


Requisition ID: 8881