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Research Associate

Requisition ID:  1429

Newcastle, GB

Contract Type:  Fixed Term
Posted Date: 


We are a world class research-intensive university. We deliver teaching and learning of the highest quality. We play a leading role in economic, social and cultural development of the North East of England. Attracting and retaining high-calibre people is fundamental to our continued success.


Salary: £31,866.00 - £40,322.00 

Closing Date: 23 March 2020

The Role


Transcription is coupled with translation in bacteria, and with splicing in eukaryotes. These interactions are critical for regulation of gene expression. However, their molecular mechanisms are obscure.


We are looking to recruit several enthusiastic and highly motivated post-doctoral Research Associates in the laboratory of Professor Nikolay Zenkin to study biochemical and structural basis of transcription/translation coupling in bacteria and its involvement in bacterial chromosome organisation, and transcription/splicing coupling in eukaryotes. 


You must have experience in biochemistry and/or CryoEM analysis of either: transcription, translation, splicing or molecular processes of similar complexity. You must be in possession of a PhD and a proven track record of active research. The Wellcome Trust funded posts are for 3 years, with possible extension.  The positions are based at the Centre for Bacterial Cell Biology of Newcastle University, situated in a modern building fitted with cutting edge equipment.


Informal enquiries should be directed to Professor Nikolay Zenkin (nikolay.zenkin@ncl.ac.uk)


As part of our commitment to career development for research staff, the University has developed 3 levels of research role profiles. These profiles set out firstly the generic competences and responsibilities expected of role holders at each level and secondly the general qualifications and experiences needed for entry at a particular level.


The Institute holds a silver Athena SWAN award in addition to the University’s silver award in recognition of our good employment practices for the advancement of gender equality.  The University also holds the HR Excellence in Research award for our work to support the career development of our researchers, and is a member of the Euraxess initiative supporting researchers in Europe.


Key Accountabilities


  •     Develop and carry out the specified project using appropriate techniques and equipment as outlined in the personal requirements.
  •     Plan and carry out independent original research encompassing:
  •     Investigations leading to the discovery of new knowledge
  •     Analysing and interpreting data to obtain new insights
  •     Initiate or participate in collaborations as agreed with supervisor.
  •     Provide guidance, where necessary, to other staff and students, including possible supervision of PhD, Master and undergraduate project students as agreed with supervisor.
  •     Contribute to running of the laboratory as agreed with supervisor.
  •     Write up research findings for publication and dissemination.


The Person

Knowledge, Skills & Experience


•    Protein purification and biochemical characterisation in vitro
•    General molecular biology techniques
•    Knowledge and expertise in in vitro characterisation of bacterial translation and/or transcription OR eukaryotic transcription and/or splicing OR in structural biology
•    Publications in high quality refereed Journals (and/or evidence of manuscripts in preparation or under review)

•   Experience in in vitro characterisation of bacterial translation and/or transcription OR eukaryotic transcription and/or splicing OR determination of molecular structures by CryoEM
•    Experience of presenting research work at scientific meetings
•    Good information technology and computing skills


Attributes and Behaviours
•    Willingness to work flexibly by mutual arrangement
•    Clear commitment to a career in research
•    Ability to work independently or as part of a team
•    Willingness to supervise Undergraduate, Masters, and PhD students


•    PhD in relevant discipline
•    Evidence of previous high quality work in this area

Newcastle University is committed to being a fully inclusive Global University which actively recruits, supports and retains staff from all sectors of society.  We value diversity as well as celebrate, support and thrive on the contributions of all our employees and the communities they represent.  We are proud to be an equal opportunities employer and encourage applications from everybody, regardless of race, sex, ethnicity, religion, nationality, sexual orientation, age, disability, gender identity, marital status/civil partnership, pregnancy and maternity, as well as being open to flexible working practices.


Requisition ID: 1429