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Research Assistant/Associate

Requisition ID:  5936

Newcastle, GB

Contract Type:  Fixed Term
Working Pattern:  Full Time
Posted Date:  12-Jun-2021


We are a world class research-intensive university. We deliver teaching and learning of the highest quality. We play a leading role in economic, social and cultural development of the North East of England. Attracting and retaining high-calibre people is fundamental to our continued success.


Salary: Research Assistant - £28,331 - £30,046 per annum  

            Research Associate - £30,942 per annum


Closing Date: 25 June 2021




The Role


The major focus is to understand the role of PD-1 and other coreceptors in innate and adaptive immune cells. Specifically, the current project will determine the regulatory pathways that control innate and adaptive immune cell function in health and disease.


The position requires a PhD (or close to completion) in Immunology with a strong background in conducting mouse experiments. 


You will have a background in cellular immunology. You will be working with mouse tissue, high-dimensional flow cytometry analysis and cell culture on a daily basis. The project also requires the use of human samples including peripheral blood and tissue.


This post is fixed term for 1 year. 


Please contact Dr Shoba Amarnath at shoba.amarnath@newcastle.ac.uk for further information.


Key Accountabilities


  • The project, will involve understanding regulatory pathways that maintain the function of murine innate and adaptive immune cells. The individual will be expected to work independently on this research project and will perform high-throughput single cell analysis using techniques such as BD-Rhapsody.
  • You will conduct experiments which will identify new signalling pathways in T cell and ILC subsets and therefore would require background knowledge of the immune system at a doctoral level
  • Although working under the general guidance of the principal investigators, they will contribute ideas, including enhancements to the technical or methodological aspects of their studies, thus providing substantial ‘added value’
  • Determine appropriate methodologies for research, with advice and support where required
  • Assess research findings for the need/scope for further investigations
  • Contribute to the writing up of their research and its dissemination, either through seminar and conference presentations or through publications
  • Present research findings, either at conferences or through publications in reputable outlets appropriate to the discipline
  • Contribute to grant applications submitted by others and in time develop own research objectives and proposals for funding
  • May be involved in the supervision, with guidance, of final year undergraduate research projects and in providing support to postgraduate research students or Research Assistants
  • Start to develop an awareness of University structures, policies and procedures and relevant issues in the higher education, research, social and political environment
  • Begin to write, with appropriate support, proposals for individual research funding or, where funders do not permit this, contribute to the writing of collective bids
  • May contribute to events celebrating the public engagement of science/social sciences/humanities
  • Will need to work with the support staff and, on occasions, with undergraduate and postgraduate students, and interact intellectually with other academic members of the Institute

The Person (Essential)


Knowledge, Skills and Experience


  • PhD or Equivalent in Immunology or lymphocyte signalling
  • Detailed subject knowledge of Tregs, T cells and/or ILCs
  • Experience in cellular and molecular immunology techniques such as cell culture,  multi parameter flow cytometry, ELISA assays, molecular biology techniques
  • Experience in working with murine tissue, isolating and characterising immune cells from murine tissue
  • Working knowledge of laboratory Health and Safety, risk assessment, COSHH
  • High level of analytical and problem-solving capability
  • Ability to communicate complex information with clarity and to encourage the commitment of others


  • Publications in peer-reviewed journals on Immunology
  • In vivo experience, preferably with PIL A,B
  • Understanding of statistical programs such as Graph Pad Prism
  • Use of Endnote or other Reference Managers
  • Self-motivated, enthusiastic, problem solving attitude
  • Good oral and written communication skills
  • Presentations at conferences and/or high quality publications

Attributes and Behaviour


  • Aware of the ethical issues involved in their research work
  • In a position to bring individual skills and insights to the research



  • A PhD and experience in the research area required (or close to submission of PhD for Research Assistant level)



Newcastle University is committed to being a fully inclusive Global University which actively recruits, supports and retains staff from all sectors of society.  We value diversity as well as celebrate, support and thrive on the contributions of all our employees and the communities they represent.  We are proud to be an equal opportunities employer and encourage applications from everybody, regardless of race, sex, ethnicity, religion, nationality, sexual orientation, age, disability, gender identity, marital status/civil partnership, pregnancy and maternity, as well as being open to flexible working practices.


The Institute holds a silver Athena SWAN award in addition to the University’s silver award in recognition of our good employment practices for the advancement of gender equality.  The University also holds the HR Excellence in Research award for our work to support the career development of our researchers, and is a member of the Euraxess initiative supporting researchers in Europe.


Requisition ID: 5936