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Research Assistant/Associate

Requisition ID:  968

Newcastle, GB

Contract Type:  Fixed Term
Posted Date:  05-Nov-2019

We are a world class research-intensive university. We deliver teaching and learning of the highest quality. We play a leading role in economic, social and cultural development of the North East of England. Attracting and retaining high-calibre people is fundamental to our continued success.

Salary: £28,331 - £32,236 

Closing Date: 4 December 2019


The role

You will join a multidisciplinary team working on pluripotent stem cell differentiation to retinal cells and early eye development.

Specifically the post-holder will work on single cell analysis of early human eye development and validation of results by immunohistochemistry and/or RNA-Scope.

A scientific background on eye, cornea and retinal development will be essential. Applicants with skills in fetal and adult eye dissection, eye tissue processing, immunohistochemistry, RNA-scope, single cell sequencing analysis, RNA-Seq and ATAC-Seq are preferred.

This is a full time, fixed term post for the duration of 1 year.

Informal enquiries to:
For further information, please visit:


Key Accountabilities

  • Assist PDRA in single cell RNA-Seq, ATAC-Seq and spatial transcriptomics
  • Validate the results of single cell sequencing by RNA-Scope and/or IHC
  • Be involved in data analysis
  • Perform eye dissection and tissue processing
  • Regular liaison with the Principal Investigator, researchers working on this project and collaborators to ensure high quality of research and timely delivery of the project goals
  • Involvement in other ongoing eye related  project in Lako’s lab
  • Lead  on the data extraction and analysis and ensure full compliance with existing ethical regulations as appropriate
  • Lead on the production of high level scientific information including analysing, writing and presenting reports and manuscripts relevant to the eye development
  • Assist with preparation and submission of interim reports to funders
  • Continuously review the literature and technology relevant to the project and ensure that the outputs of the project are positioned appropriately in relation to other on-going work
  • Work with a broad constituency of international partners with key expertise, including patient group and commercial partners, to ensure that outputs of the project are positioned appropriately and that expected target stakeholders (scientific, clinical, industry) are engaged
  • Identify and establish key links and appropriate feedback channels with bodies important for implementation of the outputs of the project
  • Continuously review the literature and technology relevant to the project and ensure that the outputs of the project are positioned appropriately in relation to other on-going work
  • Lead on supervision of BSc, MRes and PhD students working on the exosome project


The Person (Essential)

Knowledge, Skills and Experience

  • Experience in relevant research fields e.g. eye/cornea/retina development
  • Evidence of a record of research including publication and presentation of data at conferences
  • Experience of the supervision of other members of staff       
  • Experience of  eye dissection and tissue processing   
  • Experience in molecular biology          
  • Experience of immunocytochemistry  
  • Experience at post-doctoral level or equivalent with a substantial research background
  • Experience of the supervision of other members of staff

Attributes and Behaviour

  • High level laboratory skills       
  • High level administrative skills 
  • Excellent organisation  
  • Attention to detail
  • International and national travel
  • Highly Motivated and enthusiastic
  • Willingness to work outside normal hours and weekends as necessary



  • Bachelor’s degree (or equivalent) in a science or health-related subject
  • PhD in a relevant subject area (or working towards PhD completion, writing up)

Newcastle University is committed to being a fully inclusive Global University which actively recruits, supports and retains staff from all sectors of society.  We value diversity as well as celebrate, support and thrive on the contributions of all our employees and the communities they represent.  We are proud to be an equal opportunities employer and encourage applications from everybody, regardless of race, sex, ethnicity, religion, nationality, sexual orientation, age, disability, gender identity, marital status/civil partnership, pregnancy and maternity, as well as being open to flexible working practices.


Requisition ID: 968