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Research Assistant/Associate in Dermatogenetics

Requisition ID:  17186

Newcastle, GB

Contract Type:  Fixed Term
Working Pattern:  Full Time
Posted Date:  06-May-2022


We are a world class research-intensive university. We deliver teaching and learning of the highest quality. We play a leading role in economic, social and cultural development of the North East of England. Attracting and retaining high-calibre people is fundamental to our continued success.


We understand how important the full employment package is to our colleagues at Newcastle University and we are committed to providing a great range of benefits and discounts for all.  You can learn more about what is available here on our Benefits Website page.



Research Assistant: £28,756 to £30,497 per annum

Research Associate: £31,406 to £40,927 per annum 


Closing Date: 23 May 2022


The Role

An opportunity has arisen for a highly motivated individual with a background in bioinformatics to join a diverse team of investigators exploring mechanisms of ageing in humans. The project is funded by the British Skin Foundation Trust, and will take place in the Translational and Clinical Research Institute at Newcastle University. 

The post will be led by the Rajan Lab, in collaboration with the Trost (Newcastle) and Malhotra (Barcelona) Labs, and will focus on the study of a skin tumours in a genetic condition called CYLD cutaneous syndrome (CCS).  CCS patients carry rare changes in their DNA in a gene called “CYLD”, an important ubiquitin hydrolase,  and are predisposed to develop multiple skin tumours. Our understanding as to why certain CCS skin tumours develop and what makes them grow is incomplete. You will lead a programme of research on CCS skin tumours to address these questions. 

Using cutting edge proteomic techniques on patient derived tumours and primary cell models that are established in the Trost and Rajan Labs. You will study the CCS skin tumour ubiquitome, and intracellular transport mechanisms. 


Find out more about the Faculty of Medical Sciences here.


Find out more about our Research Institutes here.


As part of our commitment to career development for research colleagues, the University has developed 3 levels of research role profiles.  These profiles set out firstly the generic competences and responsibilities expected of role holders at each level and secondly the general qualifications and experiences needed for entry at a particular level.


This post is fixed term for a period of 16 months. For informal enquiries contact Neil Rajan via email:


Key Accountabilities
•    Although working under the general guidance of an academic or Principal Investigator, the postholder will contribute ideas, including enhancements to the technical or methodological aspects of their studies, thus providing substantial 'added value' 
•    Develop and carry out the specified project using appropriate techniques and equipment as outlined in the personal requirements 
•    Determine appropriate methodologies for research, with advice and support where required
•    Contribute to grant applications submitted by others and in time develop own research objectives and proposals for funding 
•    Begin to write, with appropriate support, proposals for individual research funding or, where funders do not permit this, contribute to the writing of collective bids
•    Assess research findings for the need/scope for further investigations
•    Contribute to the writing up of their research for publication and dissemination, either through seminar and conference presentations or through publications
•    Present research findings, either at conferences or through publications in reputable outlets appropriate to the discipline
•    May be involved in the supervision, with guidance, of final year undergraduate research projects and in providing support to postgraduate research students or Research Assistants 
•    Will need to work with the support staff and, on occasions, with undergraduate and postgraduate students, and interact intellectually with other academic members of the Institute.
•    May contribute to events celebrating the public engagement of science/social sciences/humanities
•    Develop an awareness of University structures, policies and procedures and relevant issues in the higher education, research, social and political environment

The Person 


Knowledge, Skills and Experience 
•    Ability to work well as part of a team and rapidly acquire new skills
•    Detailed subject knowledge in the area of research 
•    Likelihood of advanced skills directly related to the research projects 
•    High level of analytical and problem-solving capability 
•    Ability to communicate complex information with clarity and to encourage the commitment of others 
•    Experience of research with clear transferable skills and some experience or awareness of the research environment 
•    Presentations at conferences and/or high-quality publications 
•    Experience in cell culture or primary cell culture
•    Excellent immunoblotting skills

•    Experience in spheroid and organoid culture 
•    Experience in proteomics and the study of ubiquitination 
•    Experience in matrix biology

Attributes and Behaviour
•    Demonstrates substantial bioinformatics skills applied to a broad range of computing and biological sciences
•    Keeps up to date with new / improved bioinformatics knowledge, skills, techniques and research
•    Ability to work to deadlines and manage conflicting priorities
•    Demonstrates development of intellectual independence within the particular research field and academic discipline via their outputs
•    Possesses the ability to  evaluate  concepts/theories  in  order  to  develop original solutions and particular knowledge of, and expertise in, research methodologies appropriate to their area of scholarship
•    Commitment to development to include extensive reading and literature/bioinformatics methods review to continue development as a future research leader in the specific field


•    A PhD in a relevant area (or be close to submission of a PhD for Research Assistant level)

•    Honors degree in relevant subject 


Newcastle University is committed to being a fully inclusive Global University which actively recruits, supports and retains colleagues from all sectors of society.  We value diversity as well as celebrate, support and thrive on the contributions of all our employees and the communities they represent.  We are proud to be an equal opportunities employer and encourage applications from everybody, regardless of race, sex, ethnicity, religion, nationality, sexual orientation, age, disability, gender identity, marital status/civil partnership, pregnancy and maternity, as well as being open to flexible working practices.


The University holds a silver Athena SWAN award in recognition of our good employment practices for the advancement of gender equality. The University also holds the HR Excellence in Research award for our work to support the career development of our researchers, and is a member of the Euraxess initiative supporting researchers in Europe.

Requisition ID: 17186