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Experimental Scientific Officer

Requisition ID:  5460

Newcastle, GB

Contract Type:  Open Ended
Working Pattern:  Full Time
Posted Date:  27-May-2021


We are a world class research-intensive university. We deliver teaching and learning of the highest quality. We play a leading role in economic, social and cultural development of the North East of England. Attracting and retaining high-calibre people is fundamental to our continued success.


Salary: £30,942 - £36,914, with potential progression to £44,045 per annum


Closing Date: 24 June 2021


The Role


We seek to recruit a staff scientist to bring quantitative fluorescence microscopy methods to a wide group of researchers and projects through training and collaboration. You will work across the Centre for Bacterial Cell Biology (CBCB) and the Faculty of Medical Sciences Bioimaging Facility to drive forward high resolution single cell and single molecule fluorescence microscopy. There will be a particular focus on applications of quantitative microscopy to bacterial cell biology, alongside eukaryotic cell biology projects.


You will focus on supporting and training biologists in acquiring single cell, single molecule and high throughput/ high content data, and in developing quantitative analysis workflows to analyse these data. It is expected that you will take an active scientific role in collaborative projects, for example, developing new microscopy protocols and image analysis workflows.


We are looking for a scientist who is experienced in high resolution fluorescence microscopy, eg. single cell or single molecule microscopy. You should have experience in quantitative image analysis, preferably also with proficiency in image analysis via a common scripting language, eg Python, ImageJ scripting, MATLAB.


Collaboration and training are core to this position, so enthusiasm and ability to work well with others is essential. Experience in bacteriology is not required as support wil be provided. Prior staff scientist or post-doctoral experience is not required.  A PhD (awarded or submitted by appointment date) in Biophysics, Bioimage analysis, Bacteriology, Cell Biology or other relevant field is desirable.


If you would like to discuss this post and find out more about the role, please contact Dr Séamus Holden at seamus.holden@ncl.ac.uk. All enquiries will be treated in strict confidence and will not form part of the selection decision.


In your application cover letter, please explain how you meet each of the hiring criteria listed in the Person specification below.


This appointment will be made on an open-ended contract


Key Accountabilities

•    Train and assist staff in high resolution microscopy, primarily of live bacteria. Key techniques include single cell imaging of protein organization, single molecule microscopy, TIRF microscopy and structured illumination microscopy (SIM) on inverted widefield microscopes.
•    Train staff in quantitative image analysis of fluorescence microscopy data,.
•    Establish image analysis workflows and assist staff with image analysis of microscopy data. 
•    Develop and perform custom image analyses for microscopy projects.
•    Develop automated image acquisition workflows for high throughput/ high content microscopy.
•    Deliver introductory microscopy training to new users.
•    Maintain Centre for Bacterial Cell Biology (CBCB) microscopes.
•    Administrate CBCB microscopy online booking system.


The Person 

Knowledge, Skills and Experience  

•    Experience in quantitative fluorescence microscopy. (Essential)
•    Experience in quantitative image analysis. (Essential)
•    Experience in supporting and training others. (Essential)
•    Proficient in automated image analysis via a common scripting language, eg Python, ImageJ scripting, MATLAB. (Desirable)
Attributes and Behaviour (Essential)

•    Excellent interpersonal skills (Essential)
•    Well organized, able to manage and prioritize multiple tasks. (Essential)



•    MSc/ BSc/ equivalent in field relevant to Biophysics, Bioimage analysis, Bacteriology, Cell Biology, eg. Physics, Biology, Biochemistry. (Essential)
•    PhD in Biophysics, Bioimage analysis, Bacteriology, Cell Biology or other relevant field. (Desirable)




Newcastle University is committed to being a fully inclusive Global University which actively recruits, supports and retains staff from all sectors of society.  We value diversity as well as celebrate, support and thrive on the contributions of all our employees and the communities they represent.  We are proud to be an equal opportunities employer and encourage applications from everybody, regardless of race, sex, ethnicity, religion, nationality, sexual orientation, age, disability, gender identity, marital status/civil partnership, pregnancy and maternity, as well as being open to flexible working practices.


Requisition ID: 5460