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Bioinformatics Research Assistant/Associate

Requisition ID:  16194

Newcastle, GB

Contract Type:  Fixed Term
Working Pattern:  Full Time
Posted Date:  04-May-2022

Newcastle University is committed to being a fully inclusive Global University which actively recruits, supports and retains colleagues from all sectors of society.  We value diversity as well as celebrate, support and thrive on the contributions of all our employees and the communities they represent.  We are proud to be an equal opportunities employer and encourage applications from everybody, regardless of race, sex, ethnicity, religion, nationality, sexual orientation, age, disability, gender identity, marital status/civil partnership, pregnancy and maternity, as well as being open to flexible working practices.


We understand how important the full employment package is to our colleagues at Newcastle University and we are committed to providing a great range of benefits and discounts for all.  You can learn more about what is available here on our Benefits Website page.



Research Assistant: £28,756 to £30,497 per annum

Research Associate: £31,406 to 40,927 per annum


Closing Date: 14 May 2022


The Role


We are recruiting for a Bioinformatician to join our team at the Wellcome Centre for Mitochondrial Research (WCMR, The WCMR is a world-class, multidisciplinary research centre that specialises in all aspects of mitochondrial research. The role will suit an enthusiastic, talented, and self-motivated individual with proven skills in bioinformatics and working with big data.


As the WCMR bioinformatician, you will support a range of research activities across the centre, particularly the analysis of genomic, transcriptomic and proteomic data. The role will include identifying new data-driven approaches to integrating and combining different omics layers to improve our current methodologies. You will work closely will laboratory scientists and our NHS colleagues to provide guidance on experimental design, data analysis and interpretation of omics data to facilitate interactions between wet-laboratory experiments and data interpretation to answer key questions regarding mitochondrial function and human health. 


The successful applicant will join a diverse, supportive and innovative team of researchers with extensive experience in mitochondrial biology and omics-type data sets. You will have a postgraduate qualification (e.g. MSc, MRes, PhD or equivalent) in a relevant discipline. You should also have a strong level of expertise in programming (e.g. Linux,  R or Python) and experience in the analysis of complex datasets and handling of computational biological resources.

The WCMR is committed to supporting equality, diversity and inclusion for all staff and students. Applications for part-time/flexible working are welcome; please state your desired working arrangements in your application.


More information is available here: Faculty of Medical Sciences and Wellcome Centre for Mitochondrial Research


The post is available on a full time, fixed term basis, for 2 years in the first instance. 


For informal enquiries regarding the role, please contact Dr Gavin Hudson ( and/or Dr Sarah Pickett (

Key Accountabilities

  • Experience working in high performance computing (HPC) cluster
  • Experience in analysis of large-scale omics data, including complex multistage pipeline development, reporting, and troubleshooting
  • Proficiency in programming (e.g. using Linux/Python and R), command-line applications, and programming standards such as version control


The Person 


Knowledge, Skills and Experience 

  • Extensive research within subject specialism
  • High level analytical capability
  • Experience working as a genomic data scientist in a research setting: analysing, visualising and annotating high-throughput ‘omics data and the dissemination of this data to non-informatic researchers
  • Experience working with a Unix/Linux HPC or cloud computing environment
  • Experience accessing and utilising external, publicly available datasets (e.g. Genomics England, UKBioBank and EBI)
  • An in-depth understanding of the informatics field, with an interest in the evaluation and adoption of the latest bioinformatics and computational biology methodologies, complemented by a grounded, theoretical, knowledge of genetic, cell and molecular biology


  • Experience accessing and utilising external, publicly available datasets (e.g., Genomics England, UKBioBank, EBI)
  • Familiarity with containerisation (e.g., Docker or Singularity) of informatic pipelines/workflows
  • Understanding and/or experience of complex datasets, including integration of health records or phenotypic data
  • Experience in integrative omics methodologies
  • Understanding of the application of statistical methods to omics studies
  • A familiarity with the writing of manuscripts, presentations, and funding applications
  • Experience of single-cell transcriptomic, epigenetic, proteomic, and genomic datasets


Attributes and Behaviour

  • Excellent problem solving and analytical skills, and ability to prepare and maintain detailed documentation
  • Highly motivated with excellent attention to detail, able to work on own initiative and as part of a multi-disciplinary team
  • Excellent written and oral communication skills in English, with the ability to present to technical and non-technical audiences
  • Able to work independently as well as part of a team
  • Enthusiastic and hard working
  • Willingness to work flexibly by mutual agreement


  • Experience of working in a multidisciplinary team (e.g., a team involving clinicians, scientists, etc.) and/or in wider collaborative groups


  • MRes/MSc (Research Assistant level) or PhD (Research Associate level) in bioinformatics or related field, or equivalent experience


The University holds a silver Athena SWAN award in recognition of our good employment practices for the advancement of gender equality. The University also holds the HR Excellence in Research award for our work to support the career development of our researchers, and is a member of the Euraxess initiative supporting researchers in Europe.


Requisition ID: 16194